Risk factors for preoperative seizures in meningiomas - base versus non-bases of supratentorial

Background: Meningiomas are the most frequent benign intracranial lesions. The literature review reported that 19-63% of patients with meningioma suffer from preoperative seizures, and 35% experience epileptic seizures as initial symptom. present study attempted to establish risk factors for before surgery supratentorial meningiomas. Objective: To compare predictive skull base meningiomas (SBMs), non-skull (NSBMs). Materials methods: clinical data 244 treated microsurgically between 2007 2018 were analyzed retrospectively. There two groups; Group “A” (NSBMs) “B” (SBMs). Demographic, clinical, imaging, histopathological, electroencephalographic assessed. Univariate statistical analyses performed among might correlate seizures. Results: A total a diagnosis retrospectively evaluated. mean age was 54.34 years (range 16- 84), females 165, meals 79. Of these 154 base, in 65 (42.2%), whereas, 90 32 (35.5%) groups had similar seizure occurrence relation (p=0.154, p=0.819), gender (p=0.396, p=0.445) tumor size (p=0.318,p=0.244), side(p0.836, p=0.702) B respectively. pre-op third presentation both after non-focal symptoms (FND) For symptom 49.2% versus 50.8% others, while 37.5% vs 62.5%. statistically significance PTBE pre op seizure, “A”,PTBE 93(60.4%) patients,(seizure 51patients 78.5%) (42 47.2% non-seizure), (?2=,15.356, p=0.000). “B”, 43(47.8%) 25 78.1%) vs(18 31% non-seizure),(?2=,18.328, frequently OGM (seizure 25% 13.8 without seizure) SWM 71.8% 65.5% lesser overall planum/tuberculum (seizure3.2% 20.7% non-seizure). significant relationship tumour location (SBM), (?2=5.985, p=0.050) absent “A”. (?2=1.373, p=0.503). no differences WHO grade seizure. unexpected finding this is presence neurologic deficits has been less associated groups. Careful analysis further investigation needed. Conclusion: We identified major factor group studies PTBE, meningiomas, where While other radiological histopathological non-significant. Interestingly, absence